To study the microbiological profile of urosepsis in CKD patients and its treatment

Abstract

Introduction: Prevalence of Chronic Kidney disease is increasing worldwide, owing to many associated factors like lower urinary tract obstruction, urinary stones, co-morbidities, and sepsis/ sepsis of urogenital tract. Various parameters like blood pressure, sugar, kidney function tests etc need to be monitored. As urosepsis in CKD has high mortality it is necessary that causative organisms of sepsis should be identified early and antibiotic sensitivity determined to identify resistant organisms. Hence this study was carried out to. Aim and Objective: To study the microbiological spectrum involved in urosepsis of CKD patients. To study the treatment of urosepsis in CKD patients. Materials and methods: A total of 100 CKD patients were included in the study, history and clinical examination was done and blood and urine samples sent to microbiology lab. After culture sensitivity empirical treatment was accordingly changed and results observed. Results: E.coli was the commonest organism isolated in blood and urine culture. Candida was the most common organism responsible for mortality. Cefeperozone-sulbactum and meropenem were the commonly used antibiotics to which patients responded. Conclusion: Microbiological investigations in the form of blood and urine culture are of paramount importance in early diagnosis of urosepsis in CKD patients and aids in accurate administration of antibiotics.