@article{Anuruddha Singh_Ankit Agrawal_Sadhana Sanwatsarkar_2022, title={To assessand and compare the effect of two doses of chloroprocaine with buprenorphine for saddle anaesthesia in perianal surgery}, volume={5}, url={https://ijhcr.com/index.php/ijhcr/article/view/4446}, abstractNote={<p>Introduction: Saddle block is effective in patients experiencing perianal surgery in terms of postoperative recovery and analgesic consumption within 24 hours after surgery. Chloroprocaine was developed to meet the need for a short acting local anaesthetic that is reliable and has a favorable safety profile. Objectives: To study two different doses of chloroprocaine with buprenorphine for saddle anaesthesia in perianal surgery. Material and Methods: 100 Patients of ASA Gr I & II were taken for perianal surgeries are kept in sitting position under all aseptic and antiseptic precautions SAB was given using 25/23G spinal needle in sitting position. A fixed dose of chlorprocaine with bupernorphine was injected in L4-L5 intervertebral space. Patients were assessed for pain score on VAS in post operative period.Patients were monitored for pulse , BP, respiratory rate , SPO2at regular intervals on a prestructured proforma. All the data were entered in master chart and statistically analysed. Results: Mean age of patients in Group A was 41.47 ± 9.06 years whereas in Group B was 35.66 ±12.12 years. The study groups comprised of 68 males and 32 females. Mean heart rate of patients in Group A group in preoperative was 55.52±6.14 whereas in group Group B was 54.80±5.79. Mean HR in Group A and Group B was found statistically insignificant (p=0.547). Mean SBP in Group A in preoperative was 102.9 ±22.41 and in Group B was 101.2±4.79.When we compared the mean SBP in Group A and Group B was found statistically insignificant (p=0.601) and Mean DBP in Group A in preoperative was 83.62±4.79 and in Group B was 83.12±8.7. When we compared the mean SBP in Group A and Group B it was found statistically insignificant (p=0.722). Mean RR in Group A in preoperative was 16.54 ±0.67 and Group B was 16.48 ±0.64 and Mean RR in Group A in intraoperative was 17.1 ± 0.83 and group B was 17.14±078. In our study we compared the mean time taken to achieve sensory block. In group A it was 2.54±0.50 min.. In group B the mean time taken to achieve sensory block was 2.38 ±0.49 min. It appears that 0.8ml Chloroprocaine might causes faster onset of sensory block and the difference between group A and B is statistically significant (p=0.0001). VAS score was significantly high in Group A as compared to Group B at 2nd and 6th hours respectively. Whereas VAS score was comparable at 12 and 24th hours in both the groups as revealed by insignificant p values. Conclusion: From our observations and data analysis we reach to the conclusion that for saddle block with higher dose we can allow surgery for longer time but the duration of postoperative analgesia remains same in both the groups</p>}, number={3}, journal={International Journal of Health and Clinical Research}, author={Anuruddha Singh and Ankit Agrawal and Sadhana Sanwatsarkar}, year={2022}, month={Jan.}, pages={458–461} }