TY - JOUR AU - Ragupathi Siddarth, AU - Jagadeesan Dhanasekaran, AU - Sahadevan Vijay, PY - 2021/11/21 Y2 - 2024/03/28 TI - ABO blood type and association with various cancer types: A retro- prospective study from Southern India in a tertiary care setting JF - International Journal of Health and Clinical Research JA - Int. J. Heal. Clin. Res. VL - 4 IS - 20 SE - Articles DO - UR - https://ijhcr.com/index.php/ijhcr/article/view/3252 SP - 243-246 AB - <p>Objective: The role of ABO blood group in cancer biology has been intensely studied by several investigators, and it is now widely recognized that ABO antigens are associated with the risk of developing several types of tumours, namely pancreatic and gastric cancers. Aim of our study is to find out the association of ABO blood type with different type of cancer based on site and histology. Materials and methods: Ethical approval was obtained, Patients diagnosed of carcinoma coming to radiology department for CECT was included and those with previous history of surgery done for carcinoma, follow up cases coming for CT scans were excluded. Results: Out of 501 participants, the cancer of digestive system was the most frequent diagnosis that accounted for 54% of total cancer cases, followed by genitourinary system (32%) and respiratory system (10%). Cancer of the colorectal region was the most common cancer diagnosis (accounting for 22% of total cancers), followed by stomach (10%), ovary (9%) and cervix (8%). By histology, adenocarcinoma accounted for 54.5% of total histologically confirmed cancer cases while squamous cell carcinoma and carcinomas accounted for 12% and 9% respectively. The remaining 24% of cancer cases consisted of cases with other histology types. Conclusion: The results were different from those observed in western and Asian population. So, further cross section/ cohort studies are warranted across Pan India to know the association and variation in risk of cancer types with ABO blood group</p> ER -