A study of platelet parameters on chronic cigarette smokers

Abstract

Introduction :During the last decade, it was suggested that cigarette smoking affects the blood characteristics and leads to death. There are a very few studies relating the effect of smoking on platelets. In addition, many of the studies have not compared the data with those of the non smoking control groups. Methods: After taking  inform consent from patients, this Observational & analytical study was conducted in 100 patients in each group ( 100 smokers as study group and 100 age-matched nonsmokers as control group) having age group of 18–60 years using Predesigned questionnaire &complete blood count and platelet parameters such as platelet count (PLT), platelet crit (PCT), MPV, PDW, and platelet-large cell ratio (P-LCR) were estimated using Sysmex II Autoanalyser. Results : Anthroprometric & platlet para-meters were compared . The platelet parameters between smokers and nonsmokers and shows a statistically significant increase in MPV and PDW in the smokers. Conclusion: cigarette smoking in healthy men was accompanied by significant effects on platelet indices,such as increase in the mean MPV and PDW values in comparison with nonsmokers, which were also pronounced in heavy smokers along with increase in P-LCR.