Assessment of Macrovascular Compilations in Type 2 Diabetes Mellitus Patients with Special Reference to Platelet Indices

Abstract

Introduction:Diabetes mellitus (DM) is not a single disease entity but rather a group of metabolic disorders sharing the common underlying features of hyperglycemia. Larger and younger size of the platelets are suggestive of increased risk of thrombosis and also associated with increased risk for hyperglycemic complication.Objective:To assess correlation of macrovascular complications in T2DM patients with special reference toplatelet indices(MPV).Material and method: Acrosssectional analytical study was carried out in our institution for Total of 500 subjects was enrolled in the study and presence of macrovascular complications was noted. Result:MPV is significantly higher in patients with poor glycemic control(HbA1c>7)and presence of macrovascular complications compared to patients with good glycemic control (HbA1c≤7) and absence of macrovascular complications(pvalue is<0.05which is highly significant).Conclusion:Our study showed that changes in platelet indices were found to be associated with T 2 diabetes mellitus and its macrovascular complication.Hence MPVcan be used as a simple and cost effective indicator to find the association between T2 diabetes mellitus and its macrovascular complication.