Assessment of clinical profile of acute viral hepatitis among paediatric age group patients at tertiary care centre

Abstract

Background:Viral hepatitis keeps on being a significant medical issue worldwide and India. This issue is brought about by the 5 pathogenic hepatotropic infections perceived to date: hepatitis A (HAV), E(HEV), C(HCV), B(HBV) and D(HDV) infections. Be that as it may, most successive viral operators of acute viral hepatitis with significant wellbeing trouble in India are hepatitis A infection and hepatitis E infections. Material & Methods:The present prospective study was conducted at department of pediatrics of our tertiary care hospital. The study was anobservational study conducted during a period of one year. A total of 100 children who were of age 1 to 16 years and who were diagnosed withtwo or more symptoms of loss of appetite, nausea, vomiting, pain abdomen, itching and jaundice enrolled for study. along with patients who had positive serum levels of IgM HAV, IgM HEV and IgM HCV and hepatitis B surface antigen [HBsAg] were enrolled for study. Results: In present study, out of total study participants, based on the signs and symptoms, the most common presenting symptom was jaundice present in92% patientswhich was followed by hepatomegaly present in83% patients,which was followed by dark urinepresent in 82% patientswhich was followed by loss of appetite present in 82% patients. Out of total study participants, nausea was present among 76% patientswhich was followed by vomiting present in73% patients,which was followed by feverpresent in 70% patientswhich was followed by pain abdomen present in 82% patients. Out of total study participants, loose stools was present among 54% patientswhich was followed by itching present in38% patients,which was followed by Splenomegaly present in 21% patientswhich was followed by ascites present in 14% patients.Conclusion:It's critical to make mindfulness in the general public with respect to preventive measures including accessibility of immunization particularly in rustic territory. Better sterilization, arrangement of clean drinking water appropriate sewage removal, and government funded instruction are the backbones for counteraction of HAV and HEV contamination.

Key words:Clinical profile, Viral hepatitis, hepatitis.