Evaluation of Thyroid Hormone Status in Acute ST Elevation Myocardial Infarction

Abstract

Introduction:A change in thyroid function caused by non-thyroidal illnesses is found in acute myocardial infarction (AMI), as well as malnutrition, sepsis, and surgery. The goal of this study was to discover SES in AMI and its relationship to ventricular function and CKMB. Aim: To investigate whether low T3 syndrome in Acute ST elevation MI is associated with severity of myocardial injury. Severity of MI is evaluated by Isoenzyme CKMB and echocardiography.Material and Methods:Patients with acute ST elevation MI were studied over the course of a year in a cross-sectional, observational research. The researchers looked at 40 instances of AMI in a row. On day 1 (24-36 hours following the start of chest discomfort) and day 7, the thyroid profile and CKMB levels were measured. The left ventricular function was assessed by echocardiography.Results:There was no significant difference in serum T3, T4, TSH when comparing the mean values on day 1 and day 7. There was no link between the site of AMI and T3 levels, however there was a significant correlation between LVEF (p=0.05) and T3 levels. There was also a strong negative association between CKMB and T3 levels (p=0.0001).Conclusion:The LVEF and T3 levels had a significant relationship. There's also a strong negative relationship between CKMB and T3 levels. During short-term follow-up, those SES in AMI were linked to poor LV dysfunction.ma