Crosssectional Study of AsymptomaticBacteriuria and to Establish Antimicrobial Drug Susceptibility Among Pregnant Women in Ateaching Hospital ,Telangana

Abstract

Background :Asymptomatic bacteriuria is defined as the presence of bacteria in urine without having signs and symptoms Urinary tract infection is widespread among pregnant women and is accompanying adverse maternal, fetal, and neonatal outcomes.Aim of the study : To study the prevalence of asymptomatic bacteriuria and to establish antimicrobial drug susceptibility in pregnant women attending in teaching hospital; ,Telangana. Materials and methods : Cross sectional study done on 230 early morning midstream urine samples from pregnant women who came for regular antenatal checkup for the department of Gynaecology over a period of one year ie, between August 2019 and July 2020. The samples were sended for further processing to the department of Microbiology, Shadan Institute Of Medical Sciences ,Peerancheru, Hyderabad,Telangna.Results :Prevalence of significant bacteriuria was 52.1%,Higher rate of infection was seen in 1st and 2nd trimester of pregnancies, 41.6% and 45.8%. On microscopy pus cells were seen in 79.1 % of urine samples And epithelial cells were seen in 50% samples ,rbcs 1.6%, 25% wbcs .The commonest isolated organism was E. coli in 69.1% patients followed by Klebsiella pneumonia 15%. Imepenam ,Amikacin, Gentamycin and Nitrofurantoin were found to be highly effective drugs against most of isolates from urine of pregnancies. ceftriaxone, levofloxacin revealed moderately effective against those isolates.Conclusion :The prevalence of asymptomatic bacteriuriain pregnant women in our study was 52.1% and E. coli was the dominant organism isolated. Quantitative urine culture is the ideal test for detection of asymptomatic bacteriuria . Early detection and treatment are essential to protect the health of mother and fetus.