Evaluation of BISAP Score in Predicting Outcome of Acute pancreatitis in a tertiary centre

Abstract

Introduction: Acute pancreatitis is an acute inflammation of the prior normal pancreas. Its pathogenesis involves activation of intrapancreatic digestive enzymes and injury of acinar cells. Many scoring systems are available to assess the severity of acute pancreatitis, e.g., Ranson’s criteria, Glasgow score index, APACHE II and CTSI, but they have important limitations. BISAP score appears cheap, quick, simple and hence we conducted this studyMaterial and methods: This prospective observational study was carried out in 83 patients, in SGT Medical college, Gurugram, from September 2018 to March 2021.Results: In our patients with BISAP score of 0,1 and 2, there was no organ failure or mortality. At score of 3, there was 1 (07.1%) organ failure and 1 (07.1%) mortality. At score of 4, 4 (80.0%) patients had organ failure and 1(20.0%) patient died. We observed that higher the BISAP score, higher the percentage of severity, necrosis, organ failure, mortality and hospital stay. Our study revealed that with the cutoff value set at3, BISAP score is having 39.6 % sensitivity, 92.8 % specificity, 60.3% PPV and 84.7% NPV.
Conclusion: Our study recommends that at the time of admission, if BISAP score is low, our worry is less, if BISAP score is high, we should counsel the patient and attendants about possible severity, necrosis, organ failure and mortality in acute pancreatitis. Patients should be meticulously managed. Present study concludes the increased accuracy of BISAP score for risk stratification.