Efficacy of Autologous Serum Eye Drops in Chemical Eye Injury: An Institutional Based Study

Abstract

2021 / Accepted: 01-08-2021
Abstract
Background: Ocular chemical injuries are true ophthalmic emergencies that require immediate and intensive intervention to minimize severe
complications and profound visual loss. The use of autologous serum (AS) to treat ocular chemical injuries began in 1970s. Hence; the present
study was undertaken for assessing the efficacy of autologous serum eye drops in chemical eye injury.Materials & Methods: A total of 50
patients with presence of chemical eye injury were enrolled. Written consent was obtained from all the patients after explaining in detail the
entire research protocol. Fluorescing staining scores (Fl +++, Fl ++, Fl +, Fl +/-, Fl ø) were performed at baseline and weekly during the
treatment. The patients applied the serum eye drops once every two hours for 30 and more days (50% diluted of autologous serum). All the
results were recorded in Microsoft excel sheet and were analyzed by SPSS software.Results: A total of 58 eyes of 50 patients were analyzed.
Complete epithelialization of corneal defects lasted until 6 weeks. While analyzing statistically, significant results were obtained. Conclusion:
From the above results, the authors conclude that autologous serum eye drops found to be effective in chemical eye injury and significantly
reduced the healing period.