Sublingual Versus Vaginal Misoprostol for Induction of Labour in a Tertiary Care Teaching Hospital: A Comparative Study
Keywords:
Misoprostol, Labor Induction, Sublingual & Vaginal.Abstract
Background: Sometimes it is necessary to bring on labour artificially because of safety concerns for the mother or child. Induction of labor is carried out for maternal and fetal indications. One of the most common indications is prolonged pregnancy. Subjects and Methods: Total of 54 pregnant women were randomly assigned into two groups according to inclusion and exclusion criteria: group SM: 27 pregnant women received Sublingual 50mcg misoprostol and group SV: 27 pregnant women received vaginal misoprostol 50mcg. Results: The mean Bishop was 3.57±1.24 in sublingual group and 3.84±1.36 in the vaginal group (p value 0.36). Statistically not significant association between parity and route of administration of drug. The mean number of doses required for successful induction was 1.51 in sublingual and 1.1 in the vaginal group. The mean dose required for successful induction was significantly less in the vaginal group than sublingual groups. The induction to delivery interval was significantly less in sublingual group than vaginal 12.36±5.28 and 7.24±2.46 (p<0.04). The Side effects of drugs and neonatal outcomes. Conclusion: Induction of labor, vaginal misoprostol is preferable to sublingual misoprostol when used in equivalent dosage of 50 mcg and without adding any additional burden of complication.
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