Effect of Pregnancy Induced hypertension on morphology of placenta and birth weight of newborn
Keywords:hypertension, morphology, weight & newborn
Background: Hypertensive pregnancy may be responsible for vascular damage, enhanced systemic inflammation and insulin resistance in the placenta as oxygen and nutrient transfer is impaired and oxidative stress is generated affecting the placental growth and development. Placental growth pattern in hypertensive pregnancies shows a variable pattern owing to placental insufficiency. Present study was done to investigate the morphological changes in placenta in hypertensive pregnancy. And its effect on birth weight of newborn.Material Method: The study was carried out on 80 placentae, mothers and their babies. The placentae was collected from Obstetrics and Gynaecology, Department of NSCB Medical College, Jabalpur. Out of 80 placentae 40 from Pregnancy induced hypertensive and 40 normotensive mothers. As soon as the placenta was delivered, the umblical cord was cut it was put into formal saline. It was kept in a tray, to the membranes were trimmed ofl, cord was cut about 10 cm from the insertion. The blood clots adherent to maternal surface were picked up. The placenta was then washed in plain tap water naked Eye examination was done and following variables studied.Result: A Macroscopic study of the placenta revealed placental weight, placental volume, diameter, placental thickness and number of cotyledons were less in study group. Mean placental weight in study group was 336gm and in control group was 425 (p<0.05). Mean placental volume in study group & control group were 236and352 ml respectively (p<0.05). Mean number of cotyledons were 14.7and 16 in study & control group respectively but not significant and mean diameter15.6 cms and17.05cms in study and control group. But in the present study placental thickness was not significant (p<0.539). There was a single umbilical artery present in one patient in PIH group .. There was a tendency of lowering the weight of neonate 2.1kg in study group and 2.7kg in control group (p<0.05).Conclusion: In PIH group placental changes were related with fetal outcome. Common placental changes were significant in this study.
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Copyright (c) 2021 Nisha Gajbhiye, Sachin Gajbhiye
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