A Study on the Etiology and clinical profile of patients with thrombocytopenia admitted in ICU

Abstract

Background: The present study was conducted to assess the etiology of Thrombocytopenia in various patients admitted in ICU. The proportion of patients with bleeding manifestations, The percentage of patients requiring special therapy like platelet transfusions,steroids, and length of ICU stay in patients with thrombocytopenia. Material and methods: The present study was an observational study, conducted at Department of Medicine, Mallareddy Womens Medical College, Telangana among 100 patients admitted in to ICU. Approval was taken from institutional ethical committee before starting the present study. Informed consent was obtained from the study participants before enrolling the present study subjects. Results: The commonest bleeding manifestation in patients secondary to  thrombocytopenia was Gastrointestinal bleed which was seen in 9 patients. Petechial rash was seen in 8 patients,epistaxis in 3 patients. Menorrhagia,gum bleed and hematuria was seen in one patient each. Conclusions: Majority of the bleeding occurs with platelet count less than 10,000.This study shows that Sepsis is the commonest diagnosis made in patients who are detected to have thrombocytopenia at admission to the medical ICU.