Comparison of Fasting and Postprandial Lipid Profile in Diabetic Patient and Healthy Individuals

Abstract

Objective: To compare fasting and postprandial lipid profile in healthy individuals as well as in diabetic patients. Materials and Methods: The study will be conducted which includes 30 type-2 diabetic patients diagnosis based on American Diabetes Association Guidelines and 30 healthy nondiabetic control inpatients of medicine department. Fasting and Postprandial lipid levels will be estimated in all cases and controls and blood sample will be collected from patients after an overnight (12hours) fasting and four hours (4hours) postprandial after giving fixed diet. Statistical analysis will be done on collected data. Results: Type 2 diabetes has significantly deranged fasting and postprandial lipid profile when compared with controls. In the type 2 diabetes postprandial lipid parameter were significantly increased as compared to the fasting lipid parameters, and the postprandial HDL level were significantly decreased as compared to the fasting HDL level. Conclusion: This study concludes the fasting and post-prandial lipid profile is significantly deranged in Diabetics as compared to non-diabetics. Hence diabetics patients are at increased risk of atherogenic event as compared to non-diabetics and requires rigorous control of lipid profile.