Role of culture sensitivity of semen in infertility cases

Abstract

Introduction: Infections of male urogenital tracts may contribute to male infertility. However, the effects of bacterial presence on sperm quality and fertility are controversial. Objectives: To find out whether bacterial contamination could decrease sperm quality and to find out the effect of antibiotic therapy in cases of leucocytospermia on semen quality. Methodology: This is prospective study of 25 couples of infertility who came to us in outdoor clinic during the period of July 2012 to November 2014. Results: Significant pus cells(>3 pus cell/HPF) were found in 12 (48%) patients and patients having decrease motility of 5-25 % were having significant pus cells as compared to normal patient. In this group 3 out of 4 patients (75%) having significant pus cells. As the number of pus cells increase, motility decrease. Staphylococcus aureus was the highest prevalent bacteria isolated in this study. Conclusion: Detailed semen examination should not be concentrated only on sperm count but sperm motility and pus cell should be thoroughly examined. Majority of patients having pus cells in their semen are sensitive to quinolone group of drugs. But ideally we should give appropriate drug according to culture sensitivity report of patients having significant pus cells in their semen. Patients with significant pus cells responded well with antibiotic in form of increase in motility of sperm and increase rate of conception.