Silent myocardial ischemia in patients with type 2 diabetes mellitus by a treadmill test

Abstract

Background: Silent myocardial ischemia (SMI) is common in patients with diabetes mellitus. Coronary artery disease-related mortality is the leading cause in patients with diabetes mellitus. This can be prevented by early detection and intervention. The treadmill test is the commonly used modality to detect silent myocardial ischemia. Aim: Our study aimed at detecting silent myocardial ischemia in patients with type 2 diabetes mellitus by a treadmill test. Materials and methods: Out of 205 patients enrolled in the study, 40 patients with type 2 diabetes mellitus were selected as cases as per selection criteria and 20 healthy volunteers were selected as controls. Baseline characters and risk factors were noted. Biochemical parameters were measured. A treadmill test (TMT) was done. Two patients were excluded because of inconclusive TMT results. Results: Prevalence of silent myocardial ischemia was 26.3%. A significant difference was noted between cases and controls in FBS, PPBS, HbA1C, HDL cholesterol, family history of diabetes mellitus, TMT exercise time, workload, and percentage of targeted heart rate. A significant difference was noted between TMT positive and negative patients in view of age, hypertension, smoking, duration of diabetes mellitus, TMT exercise time, and workload. Conclusion: Silent myocardial ischemia is common in patients with diabetes mellitus with Male predilection.