Histopathological Study of Non-neoplastic and Neoplastic Testicular lesions- A Retrospective study

Abstract

Introduction: Testis is affected by wide range of non-neoplastic and neoplastic lesions. Non-neoplastic lesions are more common than neoplastic ones. Despite of availability of imaging and tumour marker assays, the diagnosis of testicular lesions depends primarily on Histopathological examination. Aims and Objectives: To study the Histopathological spectrum of non-neoplastic and neoplastic testicular lesions in our institute. Material and methods: A 4-year retrospective study was undertaken in department of pathology of our institute from 1st Jan 2016- 31st Dec 2019. Results: Total 39 orchidectomy specimens were studied for age distribution and Histopathological diagnosis of lesions. Non-neoplastic lesions were noted to be more common than neoplastic ones. Amongst non-neoplastic lesions, inflammatory were more common including Epididymorchitis (17.94%), testicular abscess (10.2%), Chronic orchitis (7.69%) and granulomatous orchitis (7.69%). Spectrum of neoplastic lesions included majority Seminoma testis (7.69%) followed by malignant testicular teratoma (5.12%). Conclusion: Non-neoplastic testicular lesions are common than neoplastic lesions. Certain non-neoplastic lesions clinically mimic neoplastic ones, Histopathological examination forms mainstay for diagnosis and further treatment in such cases.

Keywords: Histopathology, Orchitis, Seminoma, Testicular lesions.