A Study to Assess the Effect of Clonidine Administration in Three Different Routes as an Adjuvantive to Bupivacaine in Spinal Anaesthesia

Abstract

Aim:The present study was undertaken to observe and compare the effectiveness of clonidine administration in three different routes as an adjuvantive to bupivacaine in spinal anaesthesia.Material and Methods: The study recruited 40 male and female patients with ASA grade score of 1 and 2 and undergoing lower abdomen surgery. Patients within the age group of 20 to 60 years were included in the study. The selected participants were randomly assigned to four groups with 10 participants in each group. All the participants underwent thorough physical examination. Demographic data of the patients were collected. Block characteristics was assessed using standard methods. Incidence of side effects also noted.Results:Weight of the participants was significantly different. Height and age of the participants was not significantly different. Block characteristics of the participants was presented in table no 2. There was a significant difference observed in sensory onset, motor onset and demand for analgesia.Conclusion: The study results confirm that all the three routes administration of clonidine was effective to cause early onset of blockage of sensory and motor conduction also causes prolonged analgesia effect. The study recommends further detailed studies in this area.