A study of Clinical profile of Alcoholic liver disease

Abstract

Background: Alcoholic liver disease (ALD) is the one of leading causes of non-communicable diseases. The morbidity and mortality associated with ALD is immense in present context. However, ALD develops with myriad of complex and interlinked etiologies. Its clinical presentation and prognosis depends on amount and duration of alcohol, age of drinking etc. on the background of genetic predisposition.Material and methods: Study was conducted on 50 patients with diagnosis of Alcoholic liver disease at Military Hospital, Agra.Observation and Result: There were 46 males and 4 females. Average age of study group was 38.6 years, indicating trend towards younger onset of ALD. There were 22% of Fatty liver, 34% of Hepatitis and 44% of Cirrhosis patients. Most frequent presentation was nausea and vomiting. Higher % of patients were consuming alcohol at night, majority of them consumed > 3 – 6 times / week, majority of them started consuming at young age of 20s and symptoms of alcoholic liver disease started at 20-40 years. Majority of them consumed alcohol in groups. Prognostic scoring in cirrhotic patients was: DF Score – 37.15, MELD score – 19.27, Child pugh score – 11.65. Pearson correlation for DF score MELD score, CP score and was 0.76, 0.67,0.82 respectively. Conclusion : Duration of alcohol and quantity of alcohol results in early onset ALD. GI symptoms predominate presentation of ALD. Ascites was the commonest complication. CP scoring was best most realistic prognostic scoring. Mortality was 20%.