A clinical and microbiological study of urinary tract infections in diabetes mellitus

Abstract

Aim & Objective: To study clinical and microbiological profile of urinary tract infections and also to determine antibiotic sensitivity pattern for isolated organisms in patients with diabetes mellitus. Methodology: It was a prospective and observational study. The present study to be conducted on diabetic patients who had pus cells of more than 10 per high power field on complete urine examination who attending general medicine OPD or admitted as in patients in Kamineni hospitals, LB Nagar, Hyderabad. Results: In our study prevalence of culture positive urinary tract infection is 44%. In our study there is higher prevalence of culture positive UTI in females (46%) compared to male patients (44%). In our study age of the patient did not show any association with culture positive UTI. In our study we found that symptoms urgency, frequency, supra pubic pain had significant association with culture positive urinary tract infection. In present study there is no association of culture positive UTI with type of diabetes, duration of diabetes and treatment modality for diabetes. Elevated HbA1c correlates with occurrence of UTI and the predisposition of the diabetic to UTI depends on the degree of glycemic control over a period of weeks to months. Achieving an HbA1c <7.0 percent appears to protect those diabetics who do not have other underlying predisposing factors for UTI. An HbA1c >8.0 percent in patients with diabetes mellitus increase the chance of developing UTI. Leucocytosis, anemia was observed significantly in the culture positive group. Conclusion: In present study there is no association of culture positive UTI with type of diabetes, duration of diabetes and treatment modality for diabetes