A Prospective Study for Analysis of Clinical, Biochemical and Microbiological Profile in Sepsis Patients Admitted in ICU at Tertiary Care Centre

Abstract

Background: Sepsis and its complications are a common cause of infectious disease illness and mortality worldwide and is a significant contributor to child death in India. Hence; the present study was undertaken with the aim of assessing Clinical, Biochemical and Microbiological Profile in Sepsis Patients Admitted in ICU at Tertiary Care Centre.Materials & methods: A total of 100 patients of sepsis who were admitted were enrolled in the present study. Blood sample for bacterial culture/sensitivity were collected and sent soon after a diagnosis is made. Complete data was obtained during the stay in the hospital from the time of diagnosis which includes the hospital stay. The patients were interviewed and underwent thorough physical examination. Their Data comprising of name, age, sex, personal, occupational and proper history was recorded on the proforma. Blood samples were obtained and complete biochemical and microbiological profile was recorded.Results: Organ dysfunction was seen in 47 percent of the patients. Among them, renal dysfunction was present in 23 percent of the patients. Positive blood culture was seen 31 percent of the patients. Acenetobacter, Citrobacter, S.aureus, Klebsiella, Pseudomonas, E.coli, Gram negative bacilli and Streptococcus species were seen in 4 patients, 6 patients, 6 patients, 4 patients, 4 patients, 3 patients, 2 patients, 4 patients and 2 patients respectively.Conclusion: Positive blood cultures were found in 31% of patients with most commonly renal involvement.