Histopathological study of bladder lesions in a population of south Rajasthan

Abstract

Background: Bladder cancer is one of the most common urological malignancies. Urinary bladder cancer is the 6th most common cancer worldwide and 9th most common cancer in India, accounting for 3.9% of cancer cases. It is more common in men than in women.Aims and Objective: 1) To study the histopathological features of various lesions in the bladder. 2) To study the frequency of different pathological lesions, particularly Papillary Urothelial Neoplasms in the urinary bladder.Material and Methods: The data from 185 patients were obtained from records of the American international institute of medical sciences, Udaipur. 170 bladder biopsy and 15 cystectomy specimen were analyzed.Results: Infiltrating urothelial carcinoma (38%)was the most common carcinoma found, followed by papillary urothelial neoplasm (20%) low malignant potential (PUNLMP), urothelial carcinoma high grade(18%), urothelial carcinoma low grade(13%), papilloma (15%) and mucinous adenocarcinoma (2%). Among infiltrating urothelial carcinoma, muscle invasion was the most common. The most common age group was 5th to 7th decades of life, and male to female ratio was 2.2:1. Hematuria was the most common symptom in both neoplastic and non-neoplastic cases.