A Prospective Comparitive Study of Intensity Modulated Radiotherapy Versus Volumetric Modulated Arc Therapy Plannng and Dosimetry in Carcinoma Cervix Patients Treated with Concurrent Chemoradiation

Abstract

Background: For patients with cervical cancer, radiation therapy improves target coverage and allows dose escalation while reducing the radiation dose to organs at risk (OARs). Aims: To study dosimetry and treatment plan of Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT ) in carcinoma cervix patients . Materials and methods: A prospective study titled was taken up in Department of Radiotherapy form September 2017 to July 2019. A total 40 patients who achieved eligibility criteria were taken into study and randomized to 2 arms .In this study 20 patients were treated with IMRT and 20 patients were treated with VMAT .Dosimetric comparision is done between these two techniques. Results: It is observed that both IMRT plans and VMAT plans showed equally conformal . Homogeneity index in both IMRT and VMAT plans is almost equal in this study. In this study Monitor Units are significantly reduced with VMAT plans ,when compared to IMRT plans. So treatment delivery time is significantly reduced with VMAT plans . In this study Dose to bladder is reduced with VMAT technique but it is not statistically significant , when compared to IMRT.Conclusion: VMAT plans are advisable in carcinoma cervix patients to achieve reduced doses to OARs and reduced treatment delivery times.