Thyroid Profile in Patients with Dysfunctional Uterine Bleeding in a Tertiary Care Hospital

Authors

  • Pullaiah Akinepalli Associate Professor, Department of Biochemistry, Government Medical College/Hospital, Nalgonda, Telangana, India
  • Praveena V Assistant Professor, Department of Biochemistry, Government Medical College/Hospital, Nalgonda, Telangana, India

Keywords:

polymenorrhagia, TSH, CLIA, Hypothyroidism, Dysfunctional Uterine Bleeding.

Abstract

Introduction: In the outpatient clinic, Dysfunctional uterine bleeding (DUB) is a common diagnosis with considerable social and economic impact, making up to 20-30% cases. Complaints of heavy menstrual bleeding significantly affect the quality of life resulting in time off work, and also leading to surgical intervention including hysterectomy and ultimately posing a significant impact on the health care system.In India, thyroid disorders are among the most common endocrine diseases .Thyroid dysfunction is usually associated with reproductive disorders. Thyroid status is assessed in the present study which can help in timely and appropriate management and will prevent most of these problems. Methods: This prospective study consisted of 100 women who presented with menorrhagia and DUB to the out-patient department of OBG at Government Gneral Hospital , Nalgonda Telangana, which is a tertiary level hospital, over a period of6Months from January 2021 to June 2021.These patients were categorized as euthyroid, subclinical hypothyroid, hypothyroid or hyperthyroid based on thyroid profile. Thyroid hormones, viz., thyroid stimulating hormone TSH, total triiodothyronine T3 and tetraiodothyronine T4, were estimated by CLIA Statistical analysis of the data was performed by using Microsoft Excel software. Results: In this study, menorrhagia was the predominant abnormality (69.2%) in cases with hypothyroidism, followed by metrorrhagia (60%). most common bleeding patterns were menorrhagia (52%) followed by Polymenorrhagia (14%) and Polymenorrhea (14%). Hypothyroidism was more prevalent among cases (80%) as compared with controls (20%). In patients with menorrhagia, 69.2 % of patients had hypothyroidism. Discussion: The study reveals that in patients with DUB, hypothyroidism and menorrhagia predominate as presenting symptoms. It can be concluded that DUB is closely associated with thyroid dysfunctions, which can be relieved by normalization of thyroid status. Conclusion: So, thyroid assessment should be routinely performed in all patients with menstrual irregularities as it is seen that menstrual irregularity precedes the occurrence of other clinical symptoms of thyroid dysfunction. This will help in early detection of the cause and prompt treatment of DUB patients.

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Published

2021-12-24

How to Cite

Pullaiah Akinepalli, & Praveena V. (2021). Thyroid Profile in Patients with Dysfunctional Uterine Bleeding in a Tertiary Care Hospital. International Journal of Health and Clinical Research, 4(23), 362–368. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/3717