Study on the effectiveness of transfusion program in dengue patients receiving platelet transfusion

Abstract

Background: Dengue infection results in a spectrum of clinical syndromes ranging from a mild flu-like illness to life-threatening dengue shock with bleeding and multi-organ failure. The present study was conducted to assess the effectiveness of transfusion program in dengue patients receiving platelet transfusion. Material and methods: The present study was conducted to assess the effectiveness of transfusion program in dengue patients receiving platelet transfusion. 200 clinically suspected cases of dengue were included in the study. Cases who were positive for dengue serological tests were included in the study. The age of the patient, duration of fever before admission, result of the dengue serological test, haematocrit and platelet count on admission and during hospitalization, presence of haemorrhagic manifestation like petechiae, haematemesis, melena, gum bleeding and epistaxis and admission of platelet transfusion were recorded and analysed. Results: In the present study 200 clinically suspected dengue cases, 184 cases were positive for dengue serological tests. Among 184 serologically posititve dengue cases, 156 cases were DF, 26 cases were DHF and 2 cases were DSS. 98 patients were males and 86 were females. 119 of the 156 cases with DF required platelet transfusion. Similarly 19 out of 26 DHF cases and both DSS cases required platelet transfusion. Information regarding clinical recovery or on post transfusion platelet increment was available in 155 cases out of 180 cases, because 4 patients died during hospitalization. Conclusion: The present study concluded that 184 cases were positive for dengue serological tests. 119 of the 156 cases with DF required platelet transfusion. Similarly 19 out of 26 DHF cases and both DSS cases required platelet transfusion. Clinical recovery or on post transfusion platelet increment occur in 155 cases out of 180 cases, because 4 patients died during hospitalization.