A cross sectional study of cognitive dysfunctions in patients with type 2 diabetes mellitus in a tertiary care hospital from Andhra Pradesh

Authors

  • Gajarao Hemanth Madhav Assistant Professor, Department of Psychiatry, Maharajah's Institute of Medical Sciences, Nellimarla, Vizianagaram, Andhra Pradesh, India
  • Angati Pavani Senior Resident, Department of Psychiatry, Mahrajah's Institute of Medical Sciences, Nellimarla, Vizianagaram, Andhra Pradesh, India
  • Bonthu Nitya Aiswarya Post Graduate, Department of Psychiatry, Mahrajah's Institute of Medical Sciences, Nellimarla, Vizianagaram, Andhra Pradesh, India

Keywords:

Diabetes mellitus, nondiabetic controls, mild cognitive impairment.

Abstract

Introduction: Diabetes mellitus (DM) represents a group of common metabolic disorders that share the phenotype of hyperglycaemia. Several types of DM exist and are caused by a complex interaction of genetics, environmental factors and lifestyle choices. The metabolic dysregulation associated with DM causes secondary pathophysiological changes in multiple organ systems. Materials and Methods: The study was a case control study which was carried out after taking informed consent. Random sampling was carried out among T2DM outpatients attending the Department of Psychiatry, Maharajah's Institute of Medical Sciences, Nellimarla, Vizianagaram, Andhra Pradesh, India during the period from February 2020 to December 2020. 100 patients with T2DM and 102 age and sex matched nondiabetic controls were selected for the study. An informed written consent was obtained from all patients prior to the study. All the participants were subjected to a face to face interview during which demographic data (age, sex, education) and medical history (vitals, years of illness, significant comorbidities) were collected. Results: The demographic characteristics of patients are presented in Figure 1 and 2. The study consisted of 62% males and 32% female participants. 70 participants were in the age group of 45-50 years, 32 were between 50-55 years, 60 were between 55-60 years and 46 were between 60-65 yrs. intergroup comparison for gender and age did not show any statistical significance. The association between the presence of T2DM and MCI done using Chi square test. 44% of diabetics had MCI while 56% of diabetics had no MCI. 24% of Non-diabetics had MCI while 76% of Non-diabetics did not have MCI. The test revealed that there was a statistically significant relation between the presence of T2DM and MCI with a P value < 0.05. Conclusion: This study established that type 2 diabetes mellitus has a significant statistical association with mild cognitive impairment. This study aims to create an awareness regarding the early neurological manifestations of this rampant disease with the use of sensitive screening tools.

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Published

2022-01-18

How to Cite

Gajarao Hemanth Madhav, Angati Pavani, & Bonthu Nitya Aiswarya. (2022). A cross sectional study of cognitive dysfunctions in patients with type 2 diabetes mellitus in a tertiary care hospital from Andhra Pradesh. International Journal of Health and Clinical Research, 5(1), 81–84. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/3941