Correlation of histopathological and cytological features in proved tubercular lymphadenitis

Abstract

Background: Changes in pattern and incidence of Tuberculosis have strikingly altered the etiology of mycobacterial lymphadenitis as children are usually more affected by atypical form while adults and geriatrics are mostly infected by M.tuberculosis.5 Diagnosis of tuberculous lymphadenitis is mostly clinical and histopathological but in some cases where microscopic appearances are not exactly typical so diagnosis becomes difficult. Material and method: The study protocol included 150 patients more than 15years belonging to both sexes. Detailed history of selected patients was taken, after this clinical examination and routine investigation were carried out. Patients below 15 years, with any chronic illness, pregnant woman, with any hepatic and renal failure were excluded from study.Result: Necrotizing granulomatous lymphadenitis was most common (66.67%) cytological diagnosis followed by granulomatous lymphadenitis (18%) and necrotizing lynmphadenitis (14.66%). Out of 150 cases 78 (52%) were positive for AFB on FNAC smears while 72 (48%) were smear negative for AFB. Lymph node biopsy was done in 42 cases. Those who were not willing common most was histopathological feature (71.4%).Conclusion: FNAC smear confirmed the diagnosis bacteriologically in 52% cases subsequent FNAC culture for AFB contributed in 11 (7.3%) cases more as an additional yield over FNAC smear.