To determine difference between pain score in total knee replacement in patient with intra operative periarticular steroid infiltration vs without periarticular steroid infiltration in 1st month of post surgery period

Abstract

Background: Total knee arthroplasty (TKA) has been much improved recently and it is regarded as one of the most common and successful surgical procedure that provides pain relief and improves function in patients with severe knee arthritis.The aim of the present study is to determine difference between pain score in total knee replacement in patient with intra operative periarticular steroid infiltration vs without periarticular steroid infiltration in 1st month of post-surgery period. Methods: There are 200 patients scheduled in the present study conducted from March 2019 to December 2020. Eligible patients included patients were between the ages of 50 and 70 years. Out of 500 patients, 200 patients were recruited, and one knee was randomly assigned to the intra operative periarticular steroid infiltration orwithout periarticular steroid infiltration. Result: For patients in the group receiving steroid injection, significantly lower pain scores from the second postoperative day were noted. The pain level was significantly lower in steroid-treated knees compared to non-steroid treated knees on the night of the operation (VAS, 1.2 vs. 2.3; p=0.021). Interestingly, rebound pain was observed in both groups 1 day after the surgery (VAS, 3.2 vs. 3.8; p=0.248). Conclusion: The present study has demonstrated the efficacy and safety of periarticular infiltration of corticosteroid, bupivacaine and epinephrine following TKA. Patients who received the steroid cocktail have reported better visual analogue pain scores and required less parenteral morphine postoperatively.