Patterns of late gadolinium enhancement in injured myocardial tissue – A descriptive single centre study

Abstract

Background: CMR and LGE MR imaging is now been increasing used in diagnosis of various cardiac diseases and the characterization of different patterns of scarring / fibrosis of myocardial tissue. Different spectrum of enhancement can be seen in many pathophysiologic conditions including ischemic and non-ischemic causes. Methods: Late gadolinium enhancement MRI was performed in 28 patients in the age group of 13- 70 years ( mean age group of 42 ) and the patterns of myocardial delayed enhancement was analyzed in the year 2020 - 2021. Results: 14 out of 28 (50%) patients demonstrated late gadolinium enhancement. 3 out 14 (21.4 %) cases were due to ischemic causes and 11 cases ( 79.6%) due to non ischemic causes. Conclusion: Imaging of myocardial disorders encompasses a large variety of conditions including both ischemic and nonischemic diseases. Cardiac MRI sequences like LGE play a critical role in establishing diagnosis, determining prognosis, and guiding therapeutic management Categorization of abnormal delayed myocardial enhancement according to location (subendocardial, transmural, subepicardial, or mesocardial) allows differentiation between ischemic (infarct-related) and nonischemic cardiomyopathies and, in cases of nonischemic cardiomyopathy, narrowing of the differential diagnosis.