A study on relationship between serum ferritin and HbA1c in type 2 diabetes mellitus

Abstract

Background & Objective: To find the association of elevated serum ferritin levels with Type 2 Diabetes Mellitus and to study the relationship between serum ferritin levels and Hba1c in type 2 Diabetes mellitus. Our objective is to assess the serum ferritin levels in type 2 diabetes patients, to determine the role of serum ferritin level as an indicator of glycaemic control like HbA1c and also as a marker of insulin resistance. Methods: Physical examination and Laboratory investigation such as FBS, PLBS, Serum ferritin, HbA1c are done in every patient and collected detailed History. Results: Most common age groups are 51-60 years and 61-70 years, majority of study population comprised of males (69%), significant difference seen with gender wise and age wise distribution of Diabetes mellitus, mean values of HbA1c is 7.26%, FBS is 151.34 mg/dl, PPBS is 209.17 mg/dl and serum ferritin is 193.78 mg/dl. Correlation between duration of Diabetes and HbA1c with serum ferritin is statistically significant with p-value <0.001. With spearman correlation it is 1.0 with serum ferritin and HbA1c shows strong positive correlation. Conclusion: In our study we conclude that elevated levels of serum ferritin seen in patients with type 2 diabetes mellitus, Diabetic patients with increased HbA1c had significant hyperferritinemia and serum ferritin can be used as marker of glycaemic control as HbA1c and also a marker of insulin resistance in Diabetic patients.