Evaluation of serum uric acid in essential hypertension
Keywords:Serum Uric Acid, Hypertension, Hyperuricemia
Background: In this study we wanted to evaluate the relationship between serum uric acid (SUA) levels and hypertension, the relation between severity of hypertension to the serum uric acid levels and the relation between duration of hypertension and serum uric acid levels. Methods: This is a case control study conducted among 100 patients of which 50 were cases and 50 controls. The study was conducted over a period of 2 years from September 2016 to September 2018 in the department of general medicine at S.V.S hospital Mahbubnagar. Results: The study showed significantly higher SUA levels in cases (7.8 ± 0.6 mg/dL) when compared to that of controls (4.3± 0.8 mg/dL) (P<0.0001). The proportions of hyperuricemia among males with and without hypertension were 88.5% and 0% respectively and similarly among females with and without hypertension were 100% and 0%. No significant correlation was found between the serum uric acid levels and severity of hypertension (P>0.05).The SUA levels in stage 2 hypertension were not significantly different among both males and females when compared to those with stage I hypertension (P>0.05). Also, there was no significant correlation was between the serum uric acid levels and duration of hypertension and (P>0.05). The SUA levels in those with duration of hypertension ≥ 5 years were not significantly different among both males and females when compared to those with duration of hypertension <5 years (P>0.05). Conclusions: Hyperuricemia is seen in hypertensives. Severity of hypertension is not related to the serum uric acid levels. Duration of hypertension had no significant impact on the serum uric acid levels.
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