Study of endometrial pathology in abnormal uterine bleeding

Abstract

Background: The histopathological diagnosis of abnormal uterine bleeding (AUB) shows spectrum of patterns and pathologist plays a vital role in the reporting of endometrium and differentiating non neoplastic lesion from neoplastic lesions, early diagnosis of precursor lesions and exclusion of malignancy. The aim of the study is to study the spectrum of endometrial patterns in women with AUB and to correlate with different age groups. Materials and methods: 780 samples of endometrium in women with AUB were received from gynecology department, processed and stained with hematoxylin and eosin, subjected to histopathological examination. Results: The peak incidence was observed in the age group 31-40 years. The common histological pattern was proliferative pattern 428(54.87%),secretory phase 174(22.30%),endometrial hyperplasia without atypia 49(6.28%),pill endometrium 34(4.35%),atrophic endometrium 32(4.10%),endometrial carcinoma 28(3.58%),inadequate sample 17(2.17%),endometrial polyps 13(1.66%),endometrial hyperplasia with atypia 3(0.38%) and tuberculous endometritis 2(0.24%).Conclusion: AUB significantly affects the quality life of women and leads to anemia. Hence histopathological examination should be considered which plays a critical role in the early diagnosis of endometrial pathology and to provide appropriate gynecological management.