Utility of T2-weighted MR imaging and DWI in differentiating benign and malignant liver lesions
Keywords:
Focal liver lesions, Apparent diffusion co-effecient, hepatocellular carcinoma, receiver operating characteristicAbstract
Liver lesions represent a heterogeneous group of pathology ranging from solitary benign lesions to multiple metastases from a variety of primary tumours. Liver lesions may be cystic liver lesions or hypervascular liver lesions or liver tumours. For optimal patient management, detection and characterization of focal liver lesions (FLL) is critical.
Magnetic resonance with diffusion weighted imaging (DWI)) is a non-invasive technique which could improve the diagnostic accuracy in differentiating between benign and malignant liver lesions by measuring their ADC values.
Therefore a study design to evaluate the contribution of imaging science towards the diagnosis of focal liver lesions. Axial sections of DWI and T2WI are obtained in patients with focal liver lesions and the sensitivity, specificity and detection rates of both the sequences are compared individually and together.
In this study we are studying characteristic features of liver lesions on T2 and DWI sequence and calculating apparent diffusion co-efficient (ADC) values of focal liver lesions.