Histopathological and clinical evaluation of Endometrium in patients of dysfunctional uterine bleeding (DUB): A cross sectional prospective study in quaternary care centre of different district of Gujarat, India
Keywords:Uterine bleeding, Proliferative phase of endometrium, Secretory phase of endometrium, Endometrial hyperplasia
Context: Dysfunctional uterine is the bleeding most common condition for which patients needs to consult gynaecologist. Evaluation of histopathological findings of endometrium in patients of DUB helps in management and counselling of patients and useful to find out the pathological incidence of organic lesions prior to surgery. Aims: The aims are to analyse the histomorphological pattern of endometrium in dysfunctional uterine bleeding (DUB), assessment of architectural evaluation of the functional endometrium and providing data with reference to subsequent treatment regimen. Methods and Material: Total of 1803 patients presenting with DUB were subjected to evaluate with gross and microscopic examination of dilatation & curettage materials and hysterectomy specimens of the patients either admitted or came in OPD at quaternary care centre of different district or specimens received from outside hospitals. Results: Out 1803 of these, 621 cases were reported as Proliferative phase of endometrium, 410 cases were reported as Secretory phase of endometrium, 271 cases were of disordered proliferative endometrium, 149 cases of Basal endometrium, 88 cases of Endometrial hyperplasia, 61 cases of Menstrual endometrium, 53 cases of Hormonal induced changes of endometrium, 44 cases of Atrophic endometrium, 26 cases of Autolytic endometrium, 26 cases were reported as Well differentiated endometrial adenocarcinoma, 18 cases of Acute endometritis and 9 cases of Menstrual with hormonal included endometrium, Secretory with autolytic endometrium, Papillary syncytial changes of endometrium and Senile cystic endometrium. Maximum cases of dysfunctional uterine bleeding (823/1803) were seen between 41-50 years of age. Most of the cases presented with menorrhagia (1045/1803). Conclusions: Evaluation of endometrium in patients of DUB helps in management and counselling of patients and useful to find out the pathological incidence of organic lesions in DUB prior to surgery.
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Copyright (c) 2022 Killol N. Desai, Vidya K. Satapara, Alpeshkumar M. Maru
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