Comparision of 1% chloroprocaine and 1% chloroprocaine with fentanyl in infraumbilical surgical procedures under spinal anaesthesia

Abstract

Background: In the ambulatory setting, day by day there is an increase in the use of spinal anaesthesia. Antioxidant- and preservative-free form of 2-chloroprocaine (1%) has been re-emerged as a short-acting local anesthetic for use in spinal anesthesia.In this study,we evaluate the efficacy of 1% Chloroprocaine and 1 % Chloroprocaine with Fentanyl in spinal anaesthesia and any untoward side effects and complications associated with the study drugs and technique. Material and Methods: For this prospective, ramdomizes ,comparative study we recruited a total of 100 adult patient for infraumblical surgeries under spinal anaesthesia were randomly divided into two groups (n=50 each).Group C (n=50) received 30 mg 1% chloroprocaine with 0.5ml normal saline and Group CF (n=50) received 30 mg 1% chloroprocaine with 25mcg Fentanyl (0.5ml). Result: Faster Onset of sensory and motor blockade was seen in the group CF duration of spinal anesthesia and sensory and motor block duration is prolonged in group CF.(p<0.001) Duration ofanalgesia was significantly prolonged in the group CF when compared to group C(87.5±11 vs132.5±4.9min p<0.001) hemodynamic parameter insignificant with less side effect in both group. Conclusion: The addition of Fentanyl to intrathecal 1% chloroprocaine will increase the duration and quality of both sensory and motor blockade in spinal anaesthesia as compared to 1% chloroprocaine alone.