Analysis of Causes and Frequency of Blood Donor Deferral in a Tertiary Centre in North India – An Insight Into The Regional Deferral Pattern
Keywords:Deferral, blood donor, temporary, permanent.
Introduction: Blood donor screening should be done through a stringent process so that it ensures blood availability and accessibility while maintaining the blood safety at the same time. Donors who get rejected in the process are called deferred donors. We, hereby aimed to assess various reasons of deferral and their relative proportions and to categorize donors according to type of deferral, age and gender. Method: We performed a retrospective analysis of data of donors who presented to Department of Immunohematology and Blood Transfusion, Lady Hardinge Medical College or at VBD Camps for a period of 20 months from January 2020 to August 2021. Rate of deferral was quantified and various causes were characterised according to gender and age. Result: A total of 19,151(18,665 males,486 females) donors presented at our centre and VBD camps, of whom 17,632(92.07%) were accepted while 1,519 were deferred. Out of total donors accepted, 17,345 were males and 287 females. The percentage of deferred donors was 7.93%. Amongst 486 females, 199 were deferred, i.e. 40.95%, while 7.07% males were deferred amongst males(1320 out of 18665). Out of total deferrals, majority i.e. 1302(85.71%) were due to temporary reasons while 217(14.29%) were deferred permanently. Overall, most common reason for deferral was low hemoglobin(514/1519 i.e. 33.84%). Amongst temporary deferrals, most common reason overall was due to low hemoglobin (514/1302, 39.48%) with low hemoglobin also being the most common reason of temporary deferral in both males(393/1111= 35.37%) and females(121/191= 63.35% ). Amongst the permanent deferrals, most common reason was due to history of High risk behaviour (46/217=21.20%). History of High risk behaviour was also the most common reason of permanent deferral in males(46/209= 22.01%) and Thyroid disorders, the most common amongst permanent deferral in females(03/08=37.5%). Majority of deferred donors belonged to the age group of 29–38 years (42.66 %). Conclusion: Estimation of incidence and causes of deferral is important to get better insight of the regional deferral pattern. Temporary causes account for the majority of deferral and such donors should be followed up for the maintenance of the VBD pool and ensuring the safety of both donors and recipients. Abbreviation: VBD= voluntary blood donation, Hb= Hemoglobin, NACO = National AIDS Control Organization. WHO= World Health Organisation.
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Copyright (c) 2022 Shruti Chauhan, Sangeeta Pahuja, Shubham Sharma, Deeksha Singh
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