A To evaluate the effects of intrathecal clonidine as adjuvant to 0.5% bupivacaine (heavy) in lower abdominal surgeries

Authors

  • Deepika Sathe Associate Professor, Department of Anaesthesiology, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Ankita Joshi Assistant Professor, Department of Anaesthesiology, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Vishwas Sathe Professor, Department of Anaesthesiology, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Aditya Semwal Junior Resident, Department of Anaesthesiology, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Rakesh Singh Assistant Professor, Department of Anaesthesiology, MGM Medical College, Navi Mumbai, Maharashtra, India

Keywords:

Spinal Anesthesia, Clonidine, Abdominal Surgery, Bupivacaine, Modified Bromage Scale, Visual Analog Score, Sedation Score

Abstract

Background -Regional anaesthesia is one of the most preferred technique for lower abdominal and lower limb surgeries. It allows the patient to remain awake and minimizes problem associated with airway management. The technique is simple to perform and the onset of anaesthesia is more rapid than epidural anaesthesia, allowing the surgical incision to be made sooner. Clonidine, an α2 adrenergic agonist, has a variety of different actions. Clonidine has antihypertensive properties and the ability to potentiate the effects of local anaesthetics[10]. Clonidine has been shown to result in the prolongation of the sensory and motor blockade and the reduction in the amount or the concentration of local anaesthetic required to produce post-operative analgesia present study was designed to evaluate the effects of clonidine as an adjuvant to 0.5% bupivacaine (heavy), given intrathecally for prolonging the duration of analgesia. Materials and Methods-Present clinical study was conducted at MGM Medical college, kamothe, Navi Mumbai, the study was undertaken to compare the efficacy of clonidine as an adjuvant to 0.5%bupivacaine (heavy) for subarachnoid block in lower abdominal surgeries. It was prospective randomised control study done on 60 patients undergoing elective lower abdominal surgeries. Onset of analgesia was assessed by loss of sensation to pin prick every 30 seconds till the level of T10 dermatome was achieved. Following scales where used to assess duration of action of the drug Modified Bromage Scale, Visual Analog Score , Sedation Score. Results and Conclusion- The prolongation in duration of analgesia in clonidine group was statistically significant (p<0.05). It also prolongs the duration of motor blockade and analgesia in addition produces sedation with haemodynamic stability.

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Published

2022-01-17

How to Cite

Deepika Sathe, Ankita Joshi, Vishwas Sathe, Aditya Semwal, & Rakesh Singh. (2022). A To evaluate the effects of intrathecal clonidine as adjuvant to 0.5% bupivacaine (heavy) in lower abdominal surgeries. International Journal of Health and Clinical Research, 5(2), 543–546. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/4596