Evaluation of urine cytology in diagnosis of bladder tumor – An institutional study of 54 cases

Abstract

Introduction: Bladder cancer is a common neoplasm in middle and old age. Urine cytology is simple quick cost effective method can be used for screening of urothelial neoplasm. It is a non invasive method with fair accuracy in high grade neoplasm. Aims & Objectives: The aim of this study was to correlate between urine cytology and histology in diagnosis of bladder tumor. Materials and methods: It was a descriptive observational study, conducted in Department of Pathology, Calcutta National Medical College & Hospital from June 2014 to May 2016. We assessed 54 cases of clinically & radiologically suspected cases of bladder tumor. All the clinical, radiological data were documented. Urine samples were processed by standard methods for Leishman & PAP stained smears. Cytological finding were reported four categories and correlated with final histological diagnosis of the bladder tumor. Results: Among the 54 total cases of bladder tumor most common were high grade urothelial carcinomas. Overall sensitivity of urine cytology was 42.86%. Sensitivity was found less in papilloma and PUNLMP. Specificity and predictive value of urine cytology were 80% and 95.45% respectively. Conclusion: Exfoliative urinary cytology represents an essential tool in diagnosis of bladder tumor with high positive predictive value though its sensitivity is low as compared to histopathology.