A clinical experience of COVID-19 patients in tertiary care center

Abstract

Background: The pandemic of COVID-19 has emerged as a global public health emergency impacting health systems across the globe. Epidemiological and epidemiological research is important. Clinical features of patients in various parts of our country with COVID-19. This study highlights clinical experience at a tertiary care centre in South India in systemic manifestations of COVID-19 patients.Materials and methods:The current study is a retrospective observational study of epidemiological features and clinical manifestations of 130 COVID-19 positive patients who presented themselves to this centre during the outbreak from July, to September  2020 in a tertiary care centre. Results: During the study period, 134 patients with SARS-CoV-2 infection were admitted. Patients of age 31-50 years males are most common group effected in study. Most of the patients had raise of IL-6 with 95% followed by Hyperferritinemia 93%, Increased D-dimer 90% and Hypoxemia 80%.Most of the patients with covid 19 suffered from secondary infection 20 patients (15%) followed by AKI and metabolic acidosis 10 cases each (7.7%).Thrombotic complications in ICU despite of anticoagulants are present in 7 patients(5.3%). 6.15% is the mortality rate with reinfection in one case. Guillain-Barre  syndrome in 2(1.5%) cases. Conclusion:The COVID-19 pandemic is an example of a multi-systemic infectious disease requiring early cooperation, especially in India, with various clinical specialties to reduce the burden of the disease.