A Hospital Based Prospective Study to Estimate the Prevalence of Thyroid Disorders in Reproductive Age Group Women with Abnormal Uterine Bleeding (AUB)

Abstract

Background: Thyroid disorders are ubiquitous and insidious in their presentation. Abnormal uterine bleeding is a common problem and its management can be complex. Thyroid hormones play a key role in the menstrual and reproductive function of women. . The aim of this study to estimate the prevalence of thyroid disorders in reproductive age group women with abnormal uterine bleeding (AUB). Materials& Methods: A hospital based prospective study done on 50 women with complaining of menstrual dysfunction in obstetrics and gynecology department in government district hospital, Sirohi, Rajasthan, India during one year period. Routine investigations like hemoglobin, platelet count, total and differential count, ESR, blood grouping and Rh typing, RBS, Serum creatinine, and thyroid profile which includes T3, T4, TSH were performed in all patients. For quantitative type of data test of significance applied was student T test and for qualitative data chi square test was applied. P value of <0.05 was considered significant. Results: Among 50 women majority of patients belong to more than 30 years (50%) age group, followed by 21 to 30 yrs age group (36%) and less than 20 years were 14%.Mean age was 32.78 years. In menorrhagic patients majority were euthyroid (14) followed by subclinical hypothyroidism (5) and in oligomenorrhoea majority were again euthyroid (6) followed by subclinical hypothyroidism (5). Conclusion: Abnormal uterine bleeding is frequently seen to be associated with thyroid dysfunction and in majority of the patients, menstrual abnormality may even precede the occurrence of other clinical signs and symptoms of thyroid dysfunction. Unless proper evaluation of thyroid function is done among these patients, we often miss an important etiology of AUB.