An Analytical study of Bacteriological Profiles in Female patients of UTI receiving Ante Natal Care

Abstract

Introduction: Urinary tract infection in pregnancy is associated with significant morbidity for both mother and baby. The combination of mechanical, hormonal and physiologic changes during pregnancy contributes to significant changes in the urinary tract, which has a profound impact on the acquisition and natural history of bacteriuria during pregnancy. This study aimed to assess bacterial profile of urinary tract infection and their antimicrobial susceptibility pattern among pregnant women attending antenatal clinic at nearby local hospitals. Methods: For the purpose of the present study, data of 100 of the randomly selected Pregnant patients ( candidates / study subjects ) was taken. This retrospective study was carried out in the Dept. of Microbiology. The urinary pathogens and their antibiotic susceptibility patterns in One year was studied from the records of Microbiology laboratory. Result: Among total samples, 45(36.2%) samples yielded significant bacterial growth. E.coli (19, 42.2 %) was isolated as predominant pathogen. 14 (73.7%) E. Coli and only 2(40%) Klebsiella were sensitive to nitrofurantoin which can be used in pregnancy. Only 2 (10.5%) E.coli were sensitive to Ampicillin with remaining 17(89.5%) being resistant. Conclusion: This study showed that prevalence of UTI in pregnant women was 36.2%. It was also observed that E.coli (42.2%) was the most frequently isolated bacteria. Due to rising antibiotic resistance among uropathogens, it is necessary to have local hospital based knowledge of the uropathogens and their antibiotic sensitivity patterns.