Breast Cancer Survival Rate of Luminal vs Non-Luminal Subtype at Prof. Dr. Margono Soekarjo Regional General Hospital Purwokerto in 2021-2023

Abstract

Introduction: Breast cancer is a malignancy that originates from breast tissue such as epithelium, ducts and breast lobules. Breast cancer often occurs at a young age, due to many risk factors including alcohol consumption, diet, radiation and family history. Based on receptor gene expression in tissues, breast cancer is classified into two, namely luminal subtypes in the form of Luminal A and Luminal B, and non luminal subtypes in the form of Positive Human Epidermal Growth Factor Receptor 2 and Triple Negative Breast Cancer (TNBC). The survival rate for each subtype has a different time, so further understanding is needed to determine the right treatment for patients. This study aims to determine the relationship between survival rate and luminal and non luminal breast cancer subtypes. Methods: This study uses secondary data, namely the medical records of breast cancer patients at Prof. Hospital. Dr. Margono Soekarjo Purwokerto. The sample in this study were breast cancer patients at RSMS for the 2021-2023 period who fit the inclusion and exclusion criteria. Results: Of the 84 samples that complied, the survival rate for patients with the luminal subtype was 52.9%, while the survival rate for the non luminal subtype was 42.4%. Conclusion: The survival rate of breast cancer patients with luminal subtype is higher than that of non luminal breast cancer patients, and there is a relationship between survival rate with luminal and non luminal subtypes.