Efficacy of antitubercular drugs in Category 1 tuberculosis patients receiving daily versus intermittent regimen

Abstract

Background:Tuberculosis is one of the major public health problem in India causing a major social and economic burden in our country.Aims &Objective:To compare the efficacy of antitubercular drugs in Category 1 tuberculosis patients receiving daily versus intermittent regimen. Methods: It was an Observational prospective study. Material:The present study was carried out at the department of Pharmacology, department of Pulmonary Medicine and the Microscopy cum DOTS center of SRMSIMS, Bareilly, Uttar Pradesh from 01/09/2014 to 31/05/2015. Hundred patients were selected from pulmonary medicine OPD for the study.Results: Out of total 100 study subjects 50 were receiving intermittent regimen as per DOTS and 50 were receiving daily regimen in OPD, difference in Sputum conversion rate at the end of intensive, non-conversion rate and default rate was not found to be statistically significant in both the groups. Conclusion: Both the intermittent and daily regimen showed equal sputum conversion and default rate.