Study of hemoglobin and MCV in type 2 diabetes mellitus patients and its correlation with complications of diabetes

Abstract

Introduction: Several hematological changes affecting the red blood cells (RBCs), white blood cells (WBCs), and the coagulation factors are shown to be directly associated with DM.Altered hematological indices are closely associated with HbA1c levels in individuals with and without diabetes and some of these parameters are associated with diabetic  complications.Objective:To study the HEMOGLOBIN and MCV in type 2 diabetes mellitus patients and to study the correlation between HEMOGLOBIN and MCVand complications in type 2 diabetes mellitus patients.Materials and methods: This cross sectional observational study was carried out in our institution for duration of 1 year.Total of 500 subjects was enrolled in the study.Detailed clinical and hematological profile including presence of diabetic  complications was noted.The data was analysed using  software Graph Pad Instat.Result:mean Hb is lower side in poor glycemic control group [p=<0.013] and with microvascular[p<0.0001} complications. and mean mcv was found slightly higher side in poor glycemic control group and with diabetic complications group.Conclusion:Our studyshow that haemoglobin is significantly associated with diabetic complications.