Clinicopathological Study of Tumours and Tumour Like Lesions of The Uterine Cervix

Abstract

Background: Cervical cancer is the most common cancer of female genital tract in India. The present study was undertaken to analyze the spectrum and incidence of various tumour and tumour like lesions of uterine cervix and study the relation with clinical and pathological characteristics. Method: A total of 415 cases of tumours of uterine cervix (ectocervix and endocervix) were studied.The clinical data was obtained from patients admitted in our hospital in Department of Gynaecology and Obstetrics.The specimens were received in different forms such as punch biopsy (381), hysterectomy (5) and polypectomy(29). These were fixed in 10% buffered formalin and were routinely processed with paraffin embedding and 3 to 5µ H and E sections were studied in all cases. Results:The majority of patients were in the age group of 41-46 years, (54.2%). Malignant tumours comprised of 367 cases (88.5%) of which majority presented in stage III disease and benign tumours comprised of 48 (11.5%) cases. The most common complaint in cases diagnosed with malignant and benign tumourswas bleeding per vaginum 135 cases (36.78%) and 23 cases (41.6%) respectively. The most common malignant tumour was keratinizing-squamous cell carcinoma (273; 81.77%) and benign tumour was endocervical polyp (31; 7.4%). Conclusion:The morphological diagnosis of uterine cervical tumours can be extremely difficult given the multitude of histopathological variants. One of the most important prognostic factors was the clinical staging of cervical tumors. Cervical biopsy is a cost effective investigation with a great bearing on the ultimate treatment and prognosis of patient.