State of the art for Linear B-cell epitope in Plasmodium falciparum according to a bibliographical investigation

Authors

  • Raúl Isea Institute of Advanced Studies Foundation, Hoyo de la Puerta, Baruta

Keywords:

B cell, Plasmodium falciparum, malaria, Similarity Index

Abstract

The goal of this investigation is to analyze the bibliographical references that are registered in the IEDB database regarding the linear B-cell epitopes responsible for Plasmodium falciparum malaria in humans during the temporal period 1984 to 2018. The geographical origin of the samples and the relevant journals were obtained for the linear B-cell epitopes in Plasmodium falciparum according to the Similarity Index. This methodology can be applied to another disease.

Author Biography

Raúl Isea, Institute of Advanced Studies Foundation, Hoyo de la Puerta, Baruta

Institute of Advanced Studies Foundation, Hoyo de la Puerta, Baruta

References

1. World malaria report 2017. Geneva: World Health Organization; 2017. Licence: CC BY-NC-SA 3.0 IGO., available at https://goo.gl/CsjaUg [Oct, 2018]
2. Gosling R, von Seidlein L. The Future of the RTS,S/AS01 Malaria Vaccine: An Alternative Development Plan. PLoS Med. 2016; 13(4): e1001994.
3. Vita R, Overton JA, Greenbaum JA, Ponomarenko J, Clark JD, Cantrell JR, Wheeler DK, Gabbard JL, Hix D, Sette A, Peters B. The immune epitope database (IEDB) 3.0. Nucleic Acids Res. 2014 Oct 9. pii: gku938.
4. Isea R, Hoebeke J, Mayo-García R. Designing a Peptide-dendrimer for Use as a Synthetic Vaccine Against Plasmodium falciparum. Am. J. Bioinform. Comput. Biol. 2013;1(1): 1-8.
Isea R. Quantitative prediction of linear B-cell epitopes (2017). Biomedical Statistics and Informatics. 2017; 2(1): 1-3.
6. Isea R. Predicción de epítopos consensos de células B lineales en Plasmodium falciparum 3D7. Vaccimonitor. 2013; 22(1): 43-46.
7. Isea R, Mayo-Garcia R, Restrepo S. Reverse vaccinology in Plasmodium falciparum 3D7. Journal of Immunological Techniques in Infectious Diseases. 2016;5: 3.

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Published

2018-11-30

How to Cite

Isea, R. (2018). State of the art for Linear B-cell epitope in Plasmodium falciparum according to a bibliographical investigation. International Journal of Health and Clinical Research, 1(1), 1–8. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/7