Assessment of clinical and pathological spectrum of necrotizing lymphadenitis
Keywords:
Epstein Barr viral lymphadenitis, Kikuchi lymphadenitis, Lupus lymphadenitis.Abstract
Background:The present study was conducted to assess the clinical and pathological spectrum of necrotizing lymphadenitis. Materials & Methods:64 cases of necrotizing lymphadenitis were involved. The lymph node biopsy tissues were formalin‑fixed, paraffin‑embedded, cut into 4‑µm thick sections and stained with haematoxylin and eosin. Results: Out of 64 cases, 34 were seen in males and 30 in females. Common etiological subtypes were Kikuchi lymphadenitis in 36, Lupus lymphadenitis in 12 and Epstein Barr viral lymphadenitis in 16 cases. The difference was significant (P< 0.05).Conclusion:The most common cause of necrotizing sialadenitis was Kikuchi lymphadenitis followed by Lupus lymphadenitis and Epstein Barr viral lymphadenitis.