Pre Renal Assessment For A Successful Kidney Transplant

Abstract

Introduction:Living donor kidney transplantation is the treatment of choice for patients with end stage kidney disease, which prevents chronic dialysis and its long term side effects. In addition to the detailed clinical history and thorough laboratory testing, anatomical assessment of kidneys, pre donation kidney volume and its function before transplantation are important factors to assess post transplant outcome. Materials and methods: Patients undergoing first renal transplant and those between age group of 18 to 60 years were included in the study. Donor kidney volume was measured ultrasonographically, from which donated kidney volume was calculated to evaluate GFR of the donated kidney from the total GFR of the donor. Estimation of recipient graft function was done using four variable abbreviated MDRD equation at 3, 6, 9 and 12 months post transplant. Results :Correlation of the donor age and donor kidney volume with recipients eGFR was done and the results were tabulated. Statistical analysis was done and correlations were seen with Pearson’s correlation coefficient. Statistical significance was defined as p value 0.05. Conclusion: Living donor kidney transplantation remains one of the vitally important treatment option for the end stage renal disease patients. Estimation of donor kidney volume, eGFR and donor age all together play an important role in post transplant graft survival and also better renal outcomes and functioning.