Comparison of the effect of positive end expiratory pressure on respiratory mechanics and arterial oxygenation in laproscopic cholecystectomy

Abstract

Objective: To study and compare the effects of PEEP on Respiratory Mechanics, Oxygenation Index and Heamodynamic changes at different intervals. Methods :This prospective study was done to evaluate the effects of extrinsic PEEP on respiratory mechanics, haemodynamics and arterial blood gases during laproscopic cholecystectomy in obese patients. Results: Primary outcome variable was ratio of arterial oxygen partial pressure to inspiratory oxygen concentration Pa02/Fi02 and other variables related to gas exchange, oxygenation, ventilation, respiratory mechanics and haemodynamics were reported separately for patients randomized to PEEP application as well as control group.  All continuous data are expressed as mean ± SD.  Comparison of two groups were done by using student's test. ConclusionPEEP improves oxygenation in morbidly obese patients without causing hemodynamic instability. This improved oxygenation persists throughout the surgery but it promptly dissipates after tracheal extubation.

Keywords:Positive End Expiratory Pressure ,Respiratory Mechanics ,Arterial Oxygenation , Laproscopic Cholecystectomy.