Diagnostic comparison of bronchial biopsy with brushing, washing, TBNA and TTNA in the evaluation of lung cancer
Keywords:Lung cancer, Bronchial Biopsy,Bronchial washing,TTNA
Introduction: Lung cancer is among the five main types of cancer leading to overall cancer mortality contributing about 1.3 million deaths/year globally. Early diagnosis and treatment of the tumor is the only hope of cure at current state of knowledge. Bronchial washing, brushing, and forceps biopsies are often combined to increase the diagnostic yields. However diagnostic tests like, transthoracic needle aspiration (TTNA), Trans bronchial needle aspiration (TBNA) and lung biopsy used if the results of the above test are negative. Aims and objectives: To compare the diagnostic yield of various bronchoscopic procedures in the evaluation of bronchogenic carcinoma. Materials and methods:The study was carried out in 50 randomly selected cases of lung malignancy proved either by Bronchial washing, bronchial brushing, endobronchial biopsy and other related procedures, who attended the Respiratory medicine department, RNT Medical College, Udaipur, Rajasthan.Results: Majority belonged to 41-60 years of age group. Male: Female ratio was 9:1. Majority of cases were smokers 41(82%). 40 (80%) cases had endoscopically visible (Central Lesion), and10 (20%) had endoscopically non-visible peripheral lesion. Squamous cell carcinoma (34%) was more common followed by adenocarcinoma (26%) and small cell carcinoma (20%).40 (65%) cases was positive by Bronchial washing, 75% (30) by Bronchial brushing, 92.5% (37) by Bronchial Biopsy. Two cases were solely confirmed by TBNA (mediastinal widening), where tracheobronchial tree were normal endoscopically.Conclusion: For central lesion, the diagnostic yield was highest with endobronchial biopsy followed by bronchial brushing, TBNA, and washing. For peripheral lesion bronchial brushing, bronchial washing and CT guided transthoracic lung biopsy was diagnostic.
How to Cite
Copyright (c) 2021 Mahendra Kumar Bainara, Neha Damor, Prem Chand
This work is licensed under a Creative Commons Attribution 4.0 International License.